Division of Cardiac Surgery, Bluhm Cardiovascular Institute of Northwestern Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Ann Thorac Surg. 2011 Mar;91(3):777-83. doi: 10.1016/j.athoracsur.2010.11.015.
Our study compared health-related quality of life (HRQOL) among cardiac surgical patient groups before and after cardiac operations for isolated surgical procedures and examined cardiac surgical patient HRQOL within the context of United States population norms.
Of 2524 patients undergoing cardiac operations, 370 underwent isolated procedures (coronary artery bypass grafting, 136; aortic valve repair or replacement, 96; mitral valve repair or replacement, 92; Maze procedures, 46) between April 18, 2004, and June 30, 2008. They completed Short Form 36 questionnaires at baseline, at 3, 6, and 12 months postoperatively, and annually thereafter. Statistical analyses included χ(2), analysis of variance, longitudinal modeling, and longitudinal multivariable analyses.
Overall, the 370 cardiac surgical patients were 61.5 ± 11.9 years old, 70% men, and 76% white. Significant baseline differences in HRQOL existed among the cardiac surgical groups. Physical and mental components of the Short Form 36 improved from baseline to within 3 to 6 months postoperatively and remained stable through 3 years for all groups. When demographic and clinical covariates were held constant, the effect of cardiac surgical type on postsurgical HRQOL changes was not significant.
HRQOL improves early after cardiac operations and remains relatively constant long-term, independently of procedure type.
本研究比较了接受单纯心脏手术患者术前和术后的健康相关生活质量（HRQOL），并考察了美国人群正常范围内心脏手术患者的 HRQOL。
2004 年 4 月 18 日至 2008 年 6 月 30 日期间，共有 2524 例患者接受了心脏手术，其中 370 例患者进行了单纯手术（冠状动脉旁路移植术 136 例，主动脉瓣修复或置换术 96 例，二尖瓣修复或置换术 92 例，迷宫手术 46 例）。这些患者在基线、术后 3、6 和 12 个月以及此后每年都完成了健康调查简表 36 项问卷。统计分析包括卡方检验、方差分析、纵向模型和纵向多变量分析。
总的来说，370 例心脏手术患者的年龄为 61.5±11.9 岁，70%为男性，76%为白人。心脏手术患者的 HRQOL 在基线时存在显著差异。健康调查简表 36 的身体和心理成分从基线到术后 3 至 6 个月内均有改善，并在所有组中持续稳定 3 年。当控制人口统计学和临床协变量时，手术类型对术后 HRQOL 变化的影响并不显著。
心脏手术后早期 HRQOL 改善，并且长期保持相对稳定，与手术类型无关。
