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非ST段抬高型急性冠状动脉综合征患者与短暂性ST段抬高患者的差异特征

[Differential characteristics of patients with acute coronary syndrome without ST-segment elevation compared to those with transient ST-segment elevation].

作者信息

Arroyo Úcar E, Domínguez-Rodríguez A, Juárez Prera R, Blanco Palacios G, Hernández García C, Carrillo-Pérez Tome M, Abreu-González P

机构信息

Servicio de Cardiología, Hospital Universitario de Canarias, Tenerife, España.

出版信息

Med Intensiva. 2011 Jun-Jul;35(5):270-3. doi: 10.1016/j.medin.2011.01.007. Epub 2011 Feb 24.

Abstract

OBJECTIVE

To evaluate different characteristics of patients with acute coronary syndrome (ACS) without ST-segment elevation compared with transient St-segment elevation.

DESIGN

An observational, prospective study.

SETTING

A 12-bed coronary care unit.

PATIENTS

Consecutive patients of ACS without persistent ST-segment elevation.

MAIN VARIABLES OF INTEREST

The population was divided intro 2 groups according to the presence of transient ST-segment elevation. Variables of interest were age, cardiovascular risk factors, troponin I and glucose concentrations on admission, coronary anatomy, left ventricular ejection fraction, inhospital mortality and drugs.

RESULTS

Patients identified as ACS with transient ST-segment elevation were significantly younger, smokers and predominantly male. At the same time, they showed a minor peak elevation of troponin I, a higher ejection fraction and, mainly single-vessel coronary disease.

CONCLUSIONS

Patients with ACS with transient ST-segment elevation differ in the type of population, myocardial damage and coronary angiographic results with respect to patients with ACS without ST-segment elevation. More research is needed to clarify whether these differences imply a different therapeutic approach.

摘要

目的

评估无ST段抬高的急性冠状动脉综合征(ACS)患者与短暂性ST段抬高患者的不同特征。

设计

一项观察性前瞻性研究。

地点

一个有12张床位的冠心病监护病房。

患者

连续入选的无持续性ST段抬高的ACS患者。

主要研究变量

根据是否存在短暂性ST段抬高将人群分为两组。研究变量包括年龄、心血管危险因素、入院时肌钙蛋白I和血糖浓度、冠状动脉解剖结构、左心室射血分数、住院死亡率和药物。

结果

被确定为伴有短暂性ST段抬高的ACS患者明显更年轻,吸烟者居多且以男性为主。同时,他们的肌钙蛋白I峰值升高较小,射血分数较高,且主要为单支冠状动脉疾病。

结论

伴有短暂性ST段抬高的ACS患者在人群类型、心肌损伤和冠状动脉造影结果方面与无ST段抬高的ACS患者不同。需要更多研究来阐明这些差异是否意味着不同的治疗方法。

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