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系统评价用于治疗前尿道狭窄的移植物增强尿道成形术技术。

A systematic review of graft augmentation urethroplasty techniques for the treatment of anterior urethral strictures.

机构信息

Royal Hallamshire Hospital, Sheffield, United Kingdom.

出版信息

Eur Urol. 2011 May;59(5):797-814. doi: 10.1016/j.eururo.2011.02.010. Epub 2011 Feb 24.

Abstract

CONTEXT

Reconstructive surgeons who perform urethroplasty have a variety of techniques in their armamentarium that may be used according to factors such as aetiology, stricture position, and length. No one technique is recommended.

OBJECTIVE

Our aim was to assess the reported outcomes of the various techniques for graft augmentation urethroplasty according to site of surgery.

EVIDENCE ACQUISITION

We performed an updated systematic review of the Medline literature from 1985 to date and classified the data according to the site of surgery and technique used. Data are also presented on the type of graft used and the follow-up methodology used by each centre.

EVIDENCE SYNTHESIS

More than 2000 anterior urethroplasty procedures have been described in the literature. When considering the bulbar urethra there is no significant difference between the average success rates of the dorsal and the ventral onlay procedures, 88.4% and 88.8% at 42.2 and 34.4 mo in 934 and 563 patients, respectively. The lateral onlay technique has only been described in six patients and has a reported success rate of 83% at 77 mo. The Asopa and Palminteri techniques have been described in 89 and 53 patients with a success rate of 86.7% and 90.1% at 28.9 and 21.9 mo, respectively. When considering penile strictures, the success rate of the two-stage penile technique is significantly better than the one-stage penile technique, 90.5% versus 75.7% as calculated for 129 and 432 patients, respectively, although the follow-up of one-stage procedures was longer at 32.8 mo compared with 22.2 mo.

CONCLUSIONS

There is no evidence in the literature of a difference between one-stage techniques for urethroplasty of the bulbar urethra. The two-stage technique has better reported outcomes than a one-stage approach for penile urethroplasty but has a shorter follow-up.

摘要

背景

进行尿道成形术的重建外科医生在他们的武器库中有多种技术可供选择,这些技术可以根据病因、狭窄位置和长度等因素使用。没有一种技术被推荐。

目的

我们的目的是根据手术部位评估各种移植物增强尿道成形术的报告结果。

证据获取

我们对从 1985 年至今的 Medline 文献进行了更新的系统回顾,并根据手术部位和使用的技术对数据进行了分类。还介绍了每个中心使用的移植物类型和随访方法。

证据综合

文献中描述了 2000 多次前尿道成形术。考虑到球部尿道,背侧和腹侧覆盖术的平均成功率没有显著差异,934 例和 563 例患者分别在 42.2 和 34.4 个月时的成功率分别为 88.4%和 88.8%。侧侧覆盖技术仅在 6 例患者中描述,报道的成功率为 77 个月时的 83%。Asopa 和 Palminteri 技术分别在 89 例和 53 例患者中描述,成功率分别为 28.9 和 21.9 个月时的 86.7%和 90.1%。考虑到阴茎狭窄,两阶段阴茎技术的成功率明显优于一阶段阴茎技术,分别为 129 例和 432 例患者的 90.5%和 75.7%,尽管一阶段手术的随访时间更长,为 32.8 个月,而两阶段手术的随访时间为 22.2 个月。

结论

文献中没有证据表明球部尿道成形术的一阶段技术之间存在差异。两阶段技术在阴茎尿道成形术中的报告结果优于一阶段方法,但随访时间较短。

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