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[辐射对拔牙创愈合时间的影响。大鼠组织形态学研究]

[The effect of radiation on the chronology of extraction wound healing. Histomorphologic study in rats].

作者信息

Raveli D B, Ferreira B A, Cordeiro R de C, Okamoto T, Gabrielli M F

机构信息

Faculdade de Odontologia de Araraquara, Universidade de São Paulo.

出版信息

Rev Odontol Univ Sao Paulo. 1990 Apr-Jun;4(2):119-25.

PMID:2135341
Abstract

The purpose of this study was to analyse histomorfologically the X-radiation influence on the chronology of wound healing of tooth extraction. Sixth young albino rats were used. After extracting the maxillary right incisors all the rats, three experimental groups were formed: the control (I) and the groups that received 1.25 Sv (II) and 1.75 Sv (III). The rats were killer at 3, 7, 14 and 28 post-operative days following the teeth extraction. The pieces obtained were submitted to routine laboratorial procedures until getting pieces stained with hematoxylin and eosin. It was concluted that: 1) there was a delay in the epithelial proliferation of the gengival mucosa o the animals submitted to X-rays, in a similar way in the two irradiated groups: 2) there was a considerable delay in the alveolar repair process in dental extraction wound; 3) this delay was more proeminent when the X-ray action was more intense.

摘要

本研究的目的是从组织形态学角度分析X射线对拔牙伤口愈合时间的影响。使用了六只年轻的白化病大鼠。拔除上颌右侧门牙后,将所有大鼠分为三个实验组:对照组(I)以及接受1.25 Sv(II)和1.75 Sv(III)辐射的组。在拔牙后的术后第3、7、14和28天处死大鼠。所获得的组织块经过常规实验室程序处理,直至获得苏木精和伊红染色的组织块。得出的结论是:1)接受X射线照射的动物牙龈黏膜上皮增殖出现延迟,两个照射组情况相似;2)拔牙伤口的牙槽修复过程出现明显延迟;3)当X射线作用更强时,这种延迟更为显著。

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