替考拉宁和比较抗菌药物对一组遗传定义的葡萄球菌的体外活性。
In vitro activity of telavancin and comparator antimicrobial agents against a panel of genetically defined staphylococci.
机构信息
Quotient BioResearch, UK.
出版信息
Diagn Microbiol Infect Dis. 2011 Mar;69(3):275-9. doi: 10.1016/j.diagmicrobio.2010.09.017.
Abstract
The in vitro activity of telavancin was determined for 94 diverse Staphylococcus spp. Telavancin had MIC(90) values of 0.5 μg/mL for methicillin-susceptible, methicillin-resistant, and vancomycin-susceptible Staphylococcus aureus, and coagulase-negative staphylococci isolates. Telavancin MICs were 0.5-1 μg/mL for vancomycin-intermediate S. aureus isolates and 2-4 μg/mL for vancomycin-resistant S. aureus strains.
摘要
研究人员测定了替拉万星对 94 株不同种类的金黄色葡萄球菌的体外活性。替拉万星对甲氧西林敏感、耐甲氧西林和万古霉素敏感的金黄色葡萄球菌以及凝固酶阴性葡萄球菌的 MIC90 值均为 0.5μg/ml。替拉万星对万古霉素中介性金黄色葡萄球菌的 MIC 值为 0.5-1μg/ml，对万古霉素耐药的金黄色葡萄球菌的 MIC 值为 2-4μg/ml。
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