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[生长抑素类似物治疗使神经内分泌肿瘤肝转移实现完全且持续缓解]

[Complete and sustained remission of liver metastases from neuroendocrine tumor with somatostatin analogue therapy].

作者信息

Raizer György, Igaz Péter, Pregun István, Dabasi Gabriella, Rácz Károly

机构信息

Semmelweis Egyetem, Általános Orvostudományi Kar, II. Belgyógyászati Klinika, Budapest.

出版信息

Orv Hetil. 2011 Mar 6;152(10):407-10. doi: 10.1556/OH.2011.29054.

Abstract

Somatostatin analogues represent a major treatment modality in the therapy of neuroendocrine tumors. Their efficacy is well documented in the inhibition of hormone secretion; however, novel data seem to underline their effectiveness in tumor regression, as well. In this report authors present a case of type 1 neuroendocrine tumors of the stomach associated with liver metastases. Somatostatin analogue treatment resulted in a complete regression of the primary tumor and the metastases within two years. This case draws attention on the importance of somatostatin analogue treatment not only in the control of hormonal symptoms but also in the inhibition of tumor growth.

摘要

生长抑素类似物是神经内分泌肿瘤治疗中的一种主要治疗方式。其在抑制激素分泌方面的疗效已有充分记录;然而,新的数据似乎也突显了它们在肿瘤消退方面的有效性。在本报告中,作者呈现了一例伴有肝转移的胃1型神经内分泌肿瘤病例。生长抑素类似物治疗导致原发肿瘤和转移灶在两年内完全消退。该病例提请注意生长抑素类似物治疗不仅在控制激素症状方面,而且在抑制肿瘤生长方面的重要性。

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