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Unexpected erythroid and cytogenetic responses after discontinuation of a short course of lenalidomide as a result of severe skin rash in a patient with 5q syndrome.

作者信息

Breccia Massimo, Cannella Laura, Latagliata Roberto, Loglisci Giuseppina, Salaroli Adriano, Santopietro Michelina, Oliva Esther N, Alimena Giuliana

机构信息

Sapienza University, Rome, Italy.

出版信息

J Clin Oncol. 2011 May 10;29(14):e402-3. doi: 10.1200/JCO.2010.33.5083. Epub 2011 Feb 28.

DOI:10.1200/JCO.2010.33.5083
PMID:21357784
Abstract
摘要

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1
Unexpected erythroid and cytogenetic responses after discontinuation of a short course of lenalidomide as a result of severe skin rash in a patient with 5q syndrome.一名5q综合征患者因严重皮疹停用短期来那度胺治疗后出现意外的红系和细胞遗传学反应。
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5q- syndrome and multiple myeloma diagnosed simultaneously and successful treated with lenalidomide.5q- 综合征与多发性骨髓瘤同时诊断，并成功接受来那度胺治疗。
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Efficacy of lenalidomide in a patient with myelodysplastic syndrome with isolated del(5q) and JAK2V617F mutation.来那度胺治疗伴有孤立性5号染色体长臂缺失（del(5q)）和JAK2 V617F突变的骨髓增生异常综合征患者的疗效
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Establishing Rps6 hemizygous mice as a model for studying how ribosomal protein haploinsufficiency impairs erythropoiesis.建立 Rps6 半合子小鼠模型，研究核糖体蛋白单倍不足如何影响红细胞生成。
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Case Rep Hematol. 2019 Nov 23;2019:5180424. doi: 10.1155/2019/5180424. eCollection 2019.
2
Long-term hematological response in a patient with 5q- syndrome after suspension of lenalidomide therapy and further improvement with deferasirox therapy.来那度胺治疗中断后5q-综合征患者的长期血液学反应及地拉罗司治疗后的进一步改善
Blood Res. 2014 Jun;49(2):130-7. doi: 10.5045/br.2014.49.2.130. Epub 2014 Jun 25.