Guthrie B L, Laws E R
Department of Neurosurgery, George Washington University Medical Center, Washington, DC.
Neurosurg Clin N Am. 1990 Jan;1(1):37-48.
Low-grade gliomas (grades I and II) are infiltrative lesions. Patients harboring these tumors follow extremely variable clinical courses. Review of current data suggests that in patients with large tumors, complete excision affords long-term survival, with or without radiation therapy. Partial excision should be followed by radiation therapy. The management of very small tumors in patients who are neurologically normal is controversial. Stereotactic technique is particularly useful in diagnosis, and often in tumor resection, in this group of patients.
低级别胶质瘤（I级和II级）为浸润性病变。患有这些肿瘤的患者临床病程差异极大。对现有数据的回顾表明，对于大肿瘤患者，无论是否接受放射治疗，完整切除均可实现长期生存。部分切除后应进行放射治疗。对于神经功能正常的患者中非常小的肿瘤的处理存在争议。立体定向技术在这类患者的诊断中特别有用，在肿瘤切除中也常常如此。
