Kulik-Rechberger Beata, Piechuta Leszek, Miotła Paweł, Skorupski Paweł, Rechberger Tomasz
Department of Pediatric Propedeutics, Medical University of Lublin, Poland.
Ginekol Pol. 2010 Nov;81(11):870-3.
The aim of this article is to present the safety and efficacy of intradetrusor botulinum toxin injections in the treatment of non-neurogenic overactive bladder in pediatric patients. The electronic database MEDLINE (1966-2009) was searched including the following entries: non-neurogenic overactive bladder and botulinum overactive bladder. Data on the investigation topic are scarce. Most of the papers concern neurogenic overactive bladder in adults, with only a few dealing with children with neurological disturbances. Therefore, the following paper presents a case of botulin toxin treatment in girl with overactive bladder. The patient did not tolerate the standard anticholinergic therapy and did not present neurollogical disturbances. Successful outcome allows us to state that intradetrusor botulinum toxin type A injection is a promising new treatment method in the refractory cases of non-neurogenic pediatric overactive bladder.
本文旨在介绍膀胱逼尿肌内注射肉毒杆菌毒素治疗小儿非神经源性膀胱过度活动症的安全性和有效性。检索了电子数据库MEDLINE（1966 - 2009年），包括以下条目：非神经源性膀胱过度活动症和肉毒杆菌膀胱过度活动症。关于该研究主题的数据很少。大多数论文关注的是成人神经源性膀胱过度活动症，只有少数涉及有神经功能障碍的儿童。因此，以下论文介绍了一例肉毒杆菌毒素治疗膀胱过度活动症女孩的病例。该患者不耐受标准抗胆碱能治疗，且没有神经功能障碍。成功的治疗结果使我们可以说，膀胱逼尿肌内注射A型肉毒杆菌毒素是治疗小儿难治性非神经源性膀胱过度活动症的一种有前景的新治疗方法。
