铂树枝状聚合物包裹纳米粒子的准弹性光散射。

Quasi-elastic light scattering of platinum dendrimer-encapsulated nanoparticles.

机构信息

Department of Chemistry and Biochemistry, Texas Materials Institute, Center for Nano and Molecular Science and Technology, The University of Texas at Austin, 1 University Station A5300, Austin, Texas 78712, United States.

出版信息

Langmuir. 2011 Apr 5;27(7):4104-9. doi: 10.1021/la1050095. Epub 2011 Mar 1.

DOI:10.1021/la1050095

PMID:21361326

Abstract

Platinum dendrimer-encapsulated nanoparticles (DENs) containing an average 147 atoms were prepared within sixth-generation, hydroxyl-terminated poly(amidoamine) dendrimers (G6-OH). The hydrodynamic radii (R(h)) of the dendrimer/nanoparticle composites (DNCs) were determined by quasi-elastic light scattering (QLS) at high (pH ∼10) and neutral pH for various salt concentrations and identities. At high pH, the size of the DNC (R(h) ∼4 nm) is close to that of the empty dendrimer. At neutral pH, the size of the DNC approximately doubles (R(h) ∼8 nm) whereas that of the empty dendrimer remains unchanged. Changes in ionic strength also alter the size of the DNCs. The increase in size of the DNC is likely due to electrostatic interactions involving the metal nanoparticle.

摘要

铂树状大分子包裹的纳米粒子（DENs），平均含有 147 个原子，被包裹在第六代，羟基末端聚（酰胺-胺）树状大分子（G6-OH）内。通过准弹性光散射（QLS）在高（pH∼10）和中性 pH 下，测定了不同盐浓度和种类下，树状大分子/纳米粒子复合材料（DNCs）的流体力学半径（R(h)）。在高 pH 时，DNC 的尺寸（R(h)∼4nm）接近空树状大分子。在中性 pH 时，DNC 的尺寸大约增加一倍（R(h)∼8nm），而空树状大分子的尺寸保持不变。离子强度的变化也会改变 DNCs 的尺寸。DNC 尺寸的增加可能是由于涉及金属纳米粒子的静电相互作用。