Biomedical Diagnostics Institute, National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Dublin 9, Ireland.
Anal Chem. 2011 Mar 15;83(6):2383-7. doi: 10.1021/ac102697c. Epub 2011 Feb 25.
Metallopolymer-gold nanocomposites have been synthesized in which the metal complex-Au nanoparticle (NP) mole ratio is systematically varied by mixing solutions of 4-(dimethylamino) pyridine protected gold nanoparticles and a Ru(bpy)(2)PVP(10) metallopolymer; bpy is 2,2'-bipyridyl and PVP is poly-(4-vinylpyridine). The impact of changing the gold nanoparticle diameter ranging from 4.0 ± 0.5 to 12.5 ± 1 nm has been investigated. The photo induced emission of the metallopolymer undergoes static quenching by the metal nanoparticles irrespective of their size. When the volume ratio of Au NP-Ru is 1, the quenching efficiency increases from 38% to 93% on going from 4.0 ± 0.5 to 12.5 ± 1 nm diameter nanoparticles while the radius of the quenching sphere remains unaffected at 75 ± 5 Å. The conductivity of thin films is initially unaffected by nanoparticle incorporation until a percolation threshold is reached at a mole ratio of 4.95 × 10(-2) after which the conductivity increases before reaching a maximum. For thin films of the nanocomposites on electrodes, the electrochemiluminescence intensity of the nanocomposite initially increases as nanoparticles are added before decreasing for the highest loadings. The electrochemiluminescence intensity increases with increasing nanoparticle diameter. The electrochemiluminescence (ECL) emission intensity of the nanocomposite formed using 12.5 nm particles at mole ratios between 5 × 10(-3) and 10 × 10(-3) is approximately 7-fold higher than that found for the parent metallopolymer. The application of these materials for low cost ECL-based point of care devices is discussed.
金属聚合物-金纳米复合材料已经被合成，其中金属配合物-金纳米粒子（NP）的摩尔比通过混合 4-（二甲氨基）吡啶保护的金纳米粒子和[Ru（bpy）（2）PVP（10）]（2+）金属聚合物的溶液来系统地改变；bpy 是 2,2'-联吡啶，PVP 是聚（4-乙烯基吡啶）。改变金纳米粒子直径（4.0 ± 0.5 至 12.5 ± 1 nm）的影响已被研究。金属纳米粒子的尺寸对金属聚合物的光致发光的静态猝灭作用。当 Au NP-Ru 的体积比为 1 时，猝灭效率从 4.0 ± 0.5 至 12.5 ± 1 nm 直径纳米粒子的 38%增加到 93%，而猝灭球的半径保持不变，仍为 75 ± 5 Å。薄膜的电导率在达到 4.95 × 10（-2）的摩尔比之前不受纳米粒子掺入的影响，之后电导率在达到最大值之前先增加。对于纳米复合材料在电极上的薄膜，纳米复合材料的电化学发光强度最初随着纳米粒子的加入而增加，然后在最高负载下减小。电化学发光强度随纳米粒子直径的增加而增加。使用 12.5nm 粒子在摩尔比为 5 × 10（-3）至 10 × 10（-3）之间形成的纳米复合材料的电化学发光（ECL）发射强度比母体金属聚合物高约 7 倍。讨论了这些材料在低成本基于 ECL 的即时护理设备中的应用。
