Yonas H
Department of Neurosurgery, Presbyterian-University Hospital, Pittsburgh, Pennsylvania.
Neurosurg Clin N Am. 1990 Apr;1(2):307-18.
Although vasospasm remains a common cause for morbidity and mortality following subarachnoid hemorrhage, new therapeutic approaches and diagnostic studies offer the hope that injury caused by this disorder can be further lessened. Current CBF technologies can help to determine whether new symptoms are caused by ischemia, as well as define the often unpredictable manner in which ischemia occurs in this disorder. The CBF measurements may also help identify the best time for surgical intervention following subarachnoid hemorrhage. In addition, CBF studies may delineate when aggressive medical therapies are indicated and when they are potentially harmful. Despite the inherent limitations, as new technologies for CBF determination become more widely available, they should play an important role in the management of patients with aneurysmal subarachnoid hemorrhage.
尽管血管痉挛仍然是蛛网膜下腔出血后发病和死亡的常见原因,但新的治疗方法和诊断研究带来了希望,即这种疾病所造成的损伤能够进一步减轻。当前的脑血流量(CBF)技术有助于确定新症状是否由缺血引起,还能明确缺血在这种疾病中通常难以预测的发生方式。CBF测量也可能有助于确定蛛网膜下腔出血后进行手术干预的最佳时机。此外,CBF研究可能会明确何时需要积极的药物治疗以及何时这些治疗可能有害。尽管存在固有局限性,但随着用于测定CBF的新技术越来越广泛地应用,它们在动脉瘤性蛛网膜下腔出血患者的管理中应发挥重要作用。