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促进脊髓损伤后再生与恢复的策略。

Strategies to promote regeneration and recovery in the injured spinal cord.

作者信息

Kliot M, Lustgarten J H

机构信息

Department of Neurosurgery, University of Washington, Seattle.

出版信息

Neurosurg Clin N Am. 1990 Jul;1(3):751-9.

PMID:2136167
Abstract

The damaged spinal cord has only a limited capacity for anatomical and functional recovery. However, a growing body of experimental work is demonstrating a potential for enhanced axonal regeneration and recovery following injury. Important pathophysiologic processes are discussed, along with strategies designed to improve outcome through the reconstruction of damaged pathways and the modulation of the spinal cord's response to the primary injury.

摘要

受损脊髓在解剖学和功能恢复方面的能力有限。然而,越来越多的实验研究表明,损伤后轴突再生和恢复具有增强的潜力。本文讨论了重要的病理生理过程,以及旨在通过重建受损通路和调节脊髓对原发性损伤的反应来改善预后的策略。

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