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威斯康星州育龄妇女和新生儿中的人类免疫缺陷病毒1型

HIV-1 among childbearing women and newborns in Wisconsin.

作者信息

Hoxie N J, Vergeront J M, Pfister J R, Hoffman G, Markwardt P A, Davis J P

机构信息

Wisconsin Division of Health, Madison.

出版信息

Wis Med J. 1990 Nov;89(11):627-31.

PMID:2136199
Abstract

To estimate the prevalence of antibody to human immunodeficiency virus-type 1 (HIV-1) among Wisconsin childbearing women (CBW), a continuous blinded HIV-1 seroprevalence survey is being conducted. This survey uses dried blood specimens obtained from infants as part of the Wisconsin Newborn Screening Program. From February 1989 through March 1990, 79,546 specimens from Wisconsin residents were tested for HIV-1 antibody, 21 (0.026%) were HIV-1 seropositive. Among specimens obtained from Milwaukee County CBW, 15 (0.076%) of 19,781 were HIV-1 seropositive compared to 6 (0.010%) of 59,765 obtained from other Wisconsin counties. After adjusting for maternal residence, Wisconsin minority CBW were six times more likely to be HIV-1 seropositive when compared to white CBW. The survey results underscore the need for strategies to prevent HIV-1 infection that focus on women of childbearing age in Wisconsin.

摘要

为了估计威斯康星州育龄妇女(CBW)中人类免疫缺陷病毒1型(HIV-1)抗体的流行率,正在进行一项持续的、盲法的HIV-1血清流行率调查。这项调查使用从婴儿身上采集的干血标本,作为威斯康星州新生儿筛查项目的一部分。从1989年2月到1990年3月,对79546份来自威斯康星州居民的标本进行了HIV-1抗体检测,其中21份(0.026%)HIV-1血清呈阳性。在从密尔沃基县育龄妇女那里获得的标本中,19781份中有15份(0.076%)HIV-1血清呈阳性,相比之下,从威斯康星州其他县获得的59765份标本中有6份(0.010%)呈阳性。在对产妇居住地进行调整后,与白人育龄妇女相比,威斯康星州少数族裔育龄妇女HIV-1血清呈阳性的可能性高出六倍。调查结果强调了在威斯康星州制定针对育龄妇女预防HIV-1感染策略的必要性。

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