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[显微镜下血尿评估的方法及当前意义]

[Methods and current significance of the evaluation of microscopic haematuria].

作者信息

Hüppe P, Wawroschek F

机构信息

Klinik und Poliklinik für Urologie, Universitätsklinikum Essen, Hufelandstraße 55, 45122 Essen, Deutschland.

出版信息

Urologe A. 2011 Mar;50(3):287-91. doi: 10.1007/s00120-010-2409-2.

Abstract

Haematuria is the main symptom of malignant diseases of the urinary tract. Hence urine analysis for the detection of microscopic haematuria is an accepted diagnostic procedure in daily urologic practice. Until now there are neither international nor national agreements relating to the definition of microscopic haematuria, the choice of verification procedures and a diagnostic algorithm. As there are diverse reasons for microscopic haematuria the extent of continuative diagnostics should be adapted to the existence of risk factors for a clinically apparent disease. Low-risk patients with asymptomatic microscopic haematuria do not necessarily have to undergo primary cystoscopy if there are no pathological findings on urine cytology or ultrasound examination. Microhaematuria in high-risk patients should lead to a more intensive evaluation of the urinary tract, which should include cystoscopy and imaging of the upper urinary tract. In the diagnostics of microhaematuria you have to be aware of that intermittent bleeding is often characteristic of urothelial malignancies. Therefore, a single negative urine analysis should not lead to abandonment of further diagnostic procedures.

摘要

血尿是泌尿系统恶性疾病的主要症状。因此,在日常泌尿外科实践中,通过尿液分析检测镜下血尿是一种公认的诊断方法。到目前为止,关于镜下血尿的定义、验证程序的选择以及诊断算法,既没有国际协议也没有国家协议。由于镜下血尿存在多种原因,后续诊断的范围应根据临床显性疾病风险因素的存在情况进行调整。如果尿细胞学检查或超声检查没有病理发现,无症状镜下血尿的低风险患者不一定必须接受初次膀胱镜检查。高风险患者的镜下血尿应促使对尿路进行更深入的评估,这应包括膀胱镜检查和上尿路成像。在镜下血尿的诊断中,必须意识到间歇性出血通常是尿路上皮恶性肿瘤的特征。因此,单次尿液分析结果为阴性不应导致放弃进一步的诊断程序。

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