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生长抑素可降低运动引起的神经肽 Y 升高。

Somatostatin reduces neuropeptide Y rise induced by physical exercise.

机构信息

Department of Internal Medicine and Biomedical Sciences, University of Parma, Italy.

出版信息

Horm Metab Res. 2011 May;43(5):361-3. doi: 10.1055/s-0031-1273681. Epub 2011 Mar 1.

Abstract

The effect of an i. v. infusion of somatostatin (SRIH) 4.1 μg/min×90 min on the basal secretion of NPY and on the NPY response to physical exercise was studied in normal men. Basal NPY secretion was not modified by SRIH infusion, whereas the NPY response to physical exercise was significantly lower in the presence of SRIH. These data suggest the involvement of a somatostatinergic mechanism in the regulation of NPY response to physical exercise.

摘要

研究了静脉内输注生长抑素(SRIH)4.1μg/min×90min 对正常男性基础 NPY 分泌和运动应激 NPY 反应的影响。SRIH 输注对基础 NPY 分泌没有影响,而运动应激 NPY 反应在 SRIH 存在时明显降低。这些数据提示生长抑素能机制参与了运动应激 NPY 反应的调节。

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