Chair and Department of Pathomorphology, Zabrze, Medical University of Silesia, Katowice, Poland.
Endokrynol Pol. 2011 Jan-Feb;62(1):88-92.
This review looks at osteonecrosis in the stomatognathic system (mainly the jaws). Osteonecrosis of the jaw (ONJ) is a rare but serious clinical condition. It affects patients treated with bisphosphonates, and also with denosumab, mainly in oncological doses. In osteoporosis, it is a problem of relatively small significance. Article presents a thorough review of this phenomenon, including its definition, pathogenesis, risk factors, prevention and treatment methods, and its incidence rate.
这篇综述探讨了口腔颌面部的骨坏死(主要是颌骨)。颌骨坏死(ONJ)是一种罕见但严重的临床情况。它影响接受双膦酸盐治疗的患者,也影响接受地舒单抗治疗的患者,主要是在肿瘤剂量下。在骨质疏松症中,它是一个相对较小的问题。本文对这一现象进行了全面的回顾,包括其定义、发病机制、危险因素、预防和治疗方法以及发病率。