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卡纳塔克邦西北部象橘(芸香科)叶片精油的化学成分及抗菌活性

Chemical composition and antimicrobial activity of the essential oil of the leaves of Feronia elephantum (Rutaceae) from north west Karnataka.

作者信息

Joshi Rajesh K, Badakar Vijayalaxmi M, Kholkute Sanjiva D, Khatib Nayeem

机构信息

Regional Medical Research Centre (Indian Council of Medical Research), Nehru Nagar, Belgaum, Karnataka-590 010, India.

出版信息

Nat Prod Commun. 2011 Jan;6(1):141-3.

Abstract

The essential oil of the leaves of Feronia elephantum Corr. was analyzed by gas chromatography and gas chromatography/mass spectrometry. The main constituents were beta-pinene (28.4%), Z-anethole (22.1%), methyl chavicol (12.0%) and E-anethole (8.1%), among thirty-three identified compounds, which represented 92.6% of the total oil. The antimicrobial activity was tested against five Gram-positive and eight Gram-negative bacteria, and four fungi. The oil was active against Micrococcus luteus (Gram-positive bacterium), Proteus mirabilis (Gram-negative bacterium), Penicillium chrysogenum and Aspergillus niger (fungi) with MIC values of 0.31 +/- 0.06, 0.52 +/- 0.10, 0.20 +/- 0.50 and 0.26 +/- 0.52 mg/mL, respectively.

摘要

对象橘(Feronia elephantum Corr.)叶片的精油进行了气相色谱和气相色谱/质谱分析。在所鉴定出的33种化合物中,主要成分是β-蒎烯(28.4%)、Z-茴香脑(22.1%)、甲基丁香酚(12.0%)和E-茴香脑(8.1%),这些成分占总精油的92.6%。测试了该精油对5种革兰氏阳性菌、8种革兰氏阴性菌和4种真菌的抗菌活性。该精油对藤黄微球菌(革兰氏阳性菌)、奇异变形杆菌(革兰氏阴性菌)、产黄青霉和黑曲霉(真菌)有活性,其最低抑菌浓度(MIC)值分别为0.31±0.06、0.52±0.10、0.20±0.50和0.26±0.52mg/mL。

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