University of Texas Southwestern Medical Center, Dallas, TX, USA.
J Am Acad Orthop Surg. 2011 Mar;19(3):163-9. doi: 10.5435/00124635-201103000-00005.
Juvenile idiopathic arthritis, formerly known as juvenile rheumatoid arthritis, is a heterogeneous group of diseases characterized by onset of chronic arthritis in childhood. Diagnosis requires onset of disease by age 16 years, persistent arthritis in any joint for ≥ 6 weeks, and exclusion of other conditions that cause arthritis (eg, infection, malignancy, acute rheumatic fever, inflammatory bowel disease). Most patients with juvenile idiopathic arthritis present with subacute arthritis with minimal pain and few constitutional symptoms. Laboratory evaluation and imaging are useful to exclude other diagnoses and establish the presence of systemic inflammation. However, these modalities are of limited value in screening for rheumatic diseases, and they may be misleading because of the high rate of false-positive results. Most rheumatologic conditions are diagnosed based on pattern recognition, which is established with a thorough history and physical examination.
幼年特发性关节炎,以前称为幼年类风湿关节炎,是一组异质性疾病,其特征为儿童期慢性关节炎发作。诊断需要满足以下标准:发病年龄<16 岁,任何关节持续关节炎≥6 周,排除引起关节炎的其他情况(如感染、恶性肿瘤、急性风湿热、炎症性肠病)。大多数幼年特发性关节炎患者表现为亚急性关节炎,疼痛轻微,全身症状较少。实验室评估和影像学检查有助于排除其他诊断并确定是否存在全身炎症。然而,这些方法在筛查风湿性疾病方面的价值有限,而且由于假阳性结果的发生率较高,这些方法可能具有误导性。大多数风湿性疾病是基于详细的病史和体格检查来进行模式识别诊断的。