Kobayashi Sei, Shimane Toshikazu, Egawa Shunya, Ono Tomohiro, Mori Tomoaki, Kamakazu Kiyoaki, Sanbe Takeyuki
Dept. of Otorhinolaryngology, Showa University, Fujigaoka Hospital.
Gan To Kagaku Ryoho. 2011 Feb;38(2):233-5.
Many reports have been published on the treatment for hypopharyngeal cancer, and the treatment modalities and results have become uniform to some extent. More specifically, reconstruction by means of free jejunal grafts has become widespread, and the results of surgical treatments have stabilized. On the other hand concurrent chemoradiotherapy has been widely performed, and the results from the standpoint of organ and function preservation have revealed the various differences between institutions. In our department, we have been using concurrent chemoradiotherapy for advanced cancer with a view to organ and function preservation. In this article, we report 6 cases with hypopharyngeal cancer treated by concurrent chemoradiotherapy with S-1 plus nedaplatin(SN therapy)in our department between January 2005 and December 2008. The complete response rate after SN therapy was 83. 3%, and the laryngeal preservation rate was 100%.
关于下咽癌的治疗已有许多报道发表，治疗方式和结果在一定程度上已趋于一致。更具体地说，采用游离空肠移植进行重建已广泛应用，手术治疗结果也已稳定。另一方面，同步放化疗已广泛开展，从器官和功能保留的角度来看，各机构的结果显示出各种差异。在我们科室，为了保留器官和功能，我们一直在对晚期癌症采用同步放化疗。在本文中，我们报告了2005年1月至2008年12月期间在我们科室采用S-1加奈达铂同步放化疗（SN疗法）治疗的6例下咽癌患者。SN疗法后的完全缓解率为83.3%，喉保留率为100%。
