抗青光眼药物对比格犬使用彩色多普勒成像检测的睫状后长动脉内侧阻力指数的影响。

Effects of anti-glaucoma drugs on resistive index of the medial long posterior ciliary artery using color Doppler imaging in Beagle dogs.

作者信息

Choi Hojung, Lee Youngwon, Yeon Seongchan, Lee Hyojong, Lee Heechun

机构信息

Department of Veterinary Medical Imaging, College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, Korea.

出版信息

J Vet Sci. 2011 Mar;12(1):99-101. doi: 10.4142/jvs.2011.12.1.99.

DOI:10.4142/jvs.2011.12.1.99

PMID:21368570

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3053475/

Abstract

Color Doppler imaging (CDI) was carried out to evaluate the effects of anti-glaucoma drugs on ophthalmic circulation using CDI-derived resistive index (RI) values. CDI was performed on nine Beagle dogs, and RI values were calculated for the medial long posterior ciliary artery before and after the administration of anti-glaucoma drugs. A significant increase in RI values was found after topical administration of levobunolol (p < 0.05) or dipivefrin (p < 0.05). Pilocarpine showed no effects on RI values after topical administration. The results suggest that some anti-glaucoma drugs could affect ophthalmic blood flow.

摘要

采用彩色多普勒成像（CDI）技术，通过CDI衍生的阻力指数（RI）值来评估抗青光眼药物对眼部循环的影响。对9只比格犬进行了CDI检查，并计算了抗青光眼药物给药前后睫状后长动脉内侧的RI值。局部应用左布诺洛尔（p < 0.05）或地匹福林（p < 0.05）后，RI值显著升高。局部应用毛果芸香碱后对RI值无影响。结果表明，某些抗青光眼药物可能会影响眼部血流。