Sambanis A, Tan S A
School of Chemical Engineering and Parker H.Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA.
Methods Mol Med. 1999;18:595-605. doi: 10.1385/0-89603-516-6:595.
Transport of nutrients and metabolites in many bioartificial tissue constructs relies exclusively on diffusion, i.e., on the presence of a concentration gradient between the inside of the construct and the surrounding milieu. A quantitative evaluation of the rate of diffusional processes is thus essential for properly designing three-dimensional cell-polymer systems, and for assessing the chemical environment at various locales within the construct.
在许多生物人工组织构建体中，营养物质和代谢产物的运输完全依赖于扩散，即构建体内部与周围环境之间存在浓度梯度。因此，对扩散过程速率进行定量评估对于合理设计三维细胞-聚合物系统以及评估构建体内不同位置的化学环境至关重要。
