Floristan Uxua, Feltes Rosa, Ramírez Paloma, Alonso Maria Luisa, De Lucas Raul
Department of Dermatology, La Paz University Hospital, Madrid, Spain.
Pediatr Dermatol. 2011 May-Jun;28(3):349-50. doi: 10.1111/j.1525-1470.2011.01234.x. Epub 2011 Mar 3.
We report a 10-year-old boy presenting with palmoplantar pustular psoriasis, resistant to topical and systemic treatments, who was successfully treated with subcutaneous etanercept (0.4 mg/kg) twice a week for 1 month. Maintenance therapy was extended for 18 months in combination with near ultraviolet light therapy without any adverse effect. Etanercept may be a safe and effective alternative for severe palmoplantar pustular psoriasis in children.
我们报告了一名10岁男孩，患有掌跖脓疱型银屑病，对局部和全身治疗均耐药，每周皮下注射两次依那西普（0.4mg/kg），持续1个月，治疗成功。维持治疗联合近紫外线光疗延长了18个月，未出现任何不良反应。依那西普可能是治疗儿童重度掌跖脓疱型银屑病的一种安全有效的替代方法。
