英格兰和威尔士仍未发现新型沙眼衣原体的迹象。

Still no evidence of new variant Chlamydia trachomatis in England and Wales.

作者信息

Alexander Sarah, Coelho da Silva Filomeno, Alhadi Fathiya, Ison Catherine

机构信息

Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency, Centre for Infections, London, NW9 5HT, UK.

出版信息

Sex Health. 2011 Mar;8(1):74-5. doi: 10.1071/SH10010.

DOI:10.1071/SH10010

Abstract

BACKGROUND

New variant Chlamydia trachomatis (nvCT) remains an important public health concern and in 2008 four cases of nvCT were reported in Scotland. The present study set out to determine whether nvCT was present in England and Wales.

METHODS

1054 clinical specimens, which had been confirmed as chlamydia positive (using an nvCT unaffected platform) at nine different diagnostic laboratories throughout England and Wales, were examined for the presence of the 377 bp nvCT deletion.

RESULTS

92% (968/1054) of specimens examined were confirmed as wild-type C. trachomatis. The remaining 86 specimens were found to be untypeable, which was probably due to low levels of DNA. No nvCT specimens were identified.

CONCLUSIONS

There is currently no evidence that nvCT is present in England and Wales; however, laboratories using nvCT-affected platform should remain vigilant.

摘要

背景

新型沙眼衣原体（nvCT）仍是一个重要的公共卫生问题，2008年苏格兰报告了4例nvCT病例。本研究旨在确定英格兰和威尔士是否存在nvCT。

方法

对在英格兰和威尔士九个不同诊断实验室被确认为衣原体阳性（使用不受nvCT影响的平台）的1054份临床标本进行检测，以确定是否存在377 bp的nvCT缺失。

结果

92%（968/1054）的检测标本被确认为野生型沙眼衣原体。其余86份标本无法分型，这可能是由于DNA水平较低。未鉴定出nvCT标本。

结论

目前没有证据表明英格兰和威尔士存在nvCT；然而，使用受nvCT影响平台的实验室应保持警惕。