Research and Development, Hologic Inc., San Diego, United States.
World Health Organization Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections (STIs), National Reference Laboratory for STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Euro Surveill. 2020 Feb;25(5). doi: 10.2807/1560-7917.ES.2020.25.5.2000038.
The Finnish new variant of (FI-nvCT) is escaping diagnostics in Finland, Norway and Sweden. We have developed and validated an Aptima-format nucleic acid amplification test (NAAT) designed specifically to detect the FI-nvCT. This NAAT has high sensitivity (100%) and specificity (100%) for the FI-nvCT strain, enabling further investigation of the geographic distribution, prevalence and transmission of this diagnostic-escape mutant in screening populations in Europe.
芬兰新变体 (FI-nvCT) 在芬兰、挪威和瑞典逃避诊断。我们开发并验证了一种专门设计用于检测 FI-nvCT 的 Aptima 格式核酸扩增检测 (NAAT)。该 NAAT 对 FI-nvCT 菌株具有高灵敏度 (100%) 和特异性 (100%)，可进一步研究该诊断逃逸突变体在欧洲筛查人群中的地理分布、流行率和传播。
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