Cardiac Surgery Unit Children's Hospital La Timone, Marseille, France.
Eur J Cardiothorac Surg. 2011 Sep;40(3):614-8. doi: 10.1016/j.ejcts.2010.12.061. Epub 2011 Mar 2.
After treatment of transposition of the great arteries (TGA), ventricular septal defect (VSD), pulmonary stenosis, or atresia by various surgical procedures, two main problems led to reoperation: RV-PA conduit or connection stenosis and subaortic stenosis. We report here our mid- and long-term experience of a technique described in 1997 using a segment of aortic autograft as a RV-PA conduit.
Between 1993 and 2005, 25 patients with TGA, VSD, PS, or atresia were corrected with a technique using an intra-ventricular rerouting with conal septum resection (as in reconstruction-endo-ventriculaire (REV)) and interposition of tubular segment of autograft aorta between RV and PA without Lecompte maneuver (as in Rastelli), using in some cases an additional monocusp patch. The patient's age at correction ranged from 2.5 months to 11 years (mean 2.2 years); seven patients were under 1 year and 13 had a previous shunt procedure. Patients were regularly followed by two-dimensional (2D) annual echocardiogram, occasionally by catheterization and more recently by MNR.
There was one postoperative death essentially due to RV failure. There was one late death after 15 years. There were 23 long-term survivors with a mean follow-up of 12.8 years. All patients were in class I category and all of them were in sinus rhythm. Three of them needed a reoperation at 4, 5, and 6 years for subaortic stenosis and one of them with abnormal chordae in the left ventricle (LV) outflow, Only one patient needed a reoperation for RV-PA stenosis, 13 years after correction done at age 2.5 months, the autograft tissue not being implied and found normal at histology. Mean RV pressure by echo at last follow-up was 41 mm Hg. Ten patients exhibit a mild-to-moderate pulmonary regurgitation. Freedom from reoperation for RV-PA obstruction is 90% at 10 and 15 years.
Compared with all other techniques (Rastelli, REV, and Nikaidoh) our autograft technique provides the best-reported outcome for RV-PA outflow freedom from reoperation, the aortic segment employed being a living tissue susceptible to growth. However, it remains most often a long-term valveless procedure and does not avoid occasional unexpected LV-AO stenosis.
大动脉转位(TGA)、室间隔缺损(VSD)、肺动脉瓣狭窄或闭锁经各种手术治疗后,有两个主要问题导致再次手术:右心室-肺动脉(RV-PA)管道或连接狭窄和主动脉瓣下狭窄。我们在此报告我们使用 1997 年描述的技术的中期和长期经验,该技术使用自体主动脉段作为 RV-PA 管道。
1993 年至 2005 年间,25 例 TGA、VSD、PS 或闭锁患者采用经心室再路由和圆锥间隔切除术(如重建-心室内(REV)),以及 RV 和 PA 之间的自体主动脉管段间插入术,不进行 Lecompte 手术(如 Rastelli 手术),在某些情况下使用额外的单瓣叶补片。患者的矫正年龄从 2.5 个月到 11 岁(平均 2.2 岁);7 例患者小于 1 岁,13 例患者有先前的分流手术。患者定期接受二维(2D)年度超声心动图检查,偶尔进行心导管检查,最近进行磁共振检查。
术后死亡 1 例,主要原因是 RV 衰竭。15 年后有 1 例晚期死亡。23 例长期存活者的平均随访时间为 12.8 年。所有患者均为 I 类,均为窦性节律。其中 3 例因主动脉瓣下狭窄分别在 4、5 和 6 岁时需要再次手术,其中 1 例左心室(LV)流出道的异常腱索。仅 1 例患者因 RV-PA 狭窄需要再次手术,该患者在 2.5 个月大时接受矫正手术,13 年后,自体移植物组织未受累,组织学检查正常。最后一次随访时,通过 echo 测量的 RV 压力为 41mmHg。10 例患者出现轻度至中度肺动脉瓣反流。RV-PA 梗阻无再手术的 10 年和 15 年生存率分别为 90%。
与所有其他技术(Rastelli、REV 和 Nikaidoh)相比,我们的自体移植物技术为 RV-PA 流出道无再手术提供了最佳报告结果,所使用的主动脉段为有生长潜力的活组织。然而,它仍然主要是一种长期无瓣手术,不能避免偶尔出现的 LV-AO 狭窄。