Institute of Health Management Research, Jaipur, India.
Indian J Public Health. 2010 Oct-Dec;54(4):179-83. doi: 10.4103/0019-557X.77256.
To describe the pattern of adherence to Highly Active Antiretroviral therapy (HAART) and ascertain the factor(s) associated with nonadherence.
This was a cross-sectional, two-site, hospital-based study. The study was undertaken in 2005; as a result of phased roll out of free HAART as part of National AIDS Control Program, patients at Lok Nayak Jai Prakash (LNJP) hospital were receiving free HAART, while patients at All India Institute of Medical Sciences (AIIMS) had to bear out-of-pocket expenses for HAART. Adherence was defined as not having missed even a single pill over the previous 4-day period on self-reporting.
Adherence at AIIMS was 47%, whereas it was 90% at LNJP. The difference was statistically significant. Multivariate analysis showed that nonadherence was associated with not having been told about the importance of HAART, having to pay out-of-pocket for HAART and reported continued risk behavior post HAART.
With the provision of free HAART, adherence is likely to be high. Emphasis should be given on simultaneous recruitment of counselors, and physicians should be made aware about the need to inquire and counsel patients against continued risk behavior.
描述高效抗逆转录病毒疗法（HAART）的依从模式，并确定与不依从相关的因素。
这是一项横断面、两地点、基于医院的研究。该研究于 2005 年进行；由于作为国家艾滋病控制计划的一部分逐步推出免费 HAART，LNJP 医院的患者接受免费 HAART，而 AIIMS 的患者必须自费 HAART。依从性定义为在过去 4 天内自我报告未错过任何一粒药物。
AIIMS 的依从性为 47%，而 LNJP 的依从性为 90%。差异具有统计学意义。多变量分析表明，不依从与未被告知 HAART 的重要性、自费 HAART 和报告 HAART 后继续存在风险行为有关。
提供免费 HAART 后，依从性可能会提高。应重视同时招募顾问，医生应意识到需要询问和劝告患者避免继续存在风险行为。
