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与金黄色葡萄球菌菌血症相关的免疫复合物性肾小球肾炎:对皮质类固醇治疗的反应

Immune complex glomerulonephritis associated with Staphylococcus aureus bacteremia: response to corticosteroid therapy.

作者信息

McKinsey D S, McMurray T I, Flynn J M

机构信息

Department of Epidemiology and Infectious Disease, Research Medical Center, Kansas City, Missouri 64132.

出版信息

Rev Infect Dis. 1990 Jan-Feb;12(1):125-7. doi: 10.1093/clinids/12.1.125.

Abstract

Immune complex glomerulonephritis developed in a patient with high-grade Staphylococcus aureus bacteremia. Renal function declined steadily despite treatment with a prolonged course of bactericidal antimicrobial agents and apparent cure of the staphylococcal infection. Following initiation of corticosteroid therapy, renal function improved dramatically. Judicious use of corticosteroids should be considered in patients with persistent renal dysfunction secondary to infection-associated immune complex glomerulonephritis.

摘要

一名患有高度金黄色葡萄球菌菌血症的患者发生了免疫复合物性肾小球肾炎。尽管使用了长疗程的杀菌性抗菌药物进行治疗且葡萄球菌感染明显治愈,但肾功能仍持续下降。在开始使用皮质类固醇治疗后,肾功能显著改善。对于继发于感染相关免疫复合物性肾小球肾炎且存在持续性肾功能不全的患者,应考虑谨慎使用皮质类固醇。

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