Kantelhardt Eva J, Thomssen Christoph
Universitätsfrauenklinik der Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Germany.
Breast Care (Basel). 2008;3(2):93-99. doi: 10.1159/000127441. Epub 2008 May 15.
Some form of standardised treatment for patients with breast cancer is probably well established in German health institutions throughout the country. Keeping standards up to date, however, is a rather complex activity involving time and financial resources. Turnover of scientific knowledge is fast and numerous. Most health care professionals will not be able to ensure such kind of evidence-based diagnostics and treatment standards of care alone. The breast commission of the German Gynaecological Oncology Working Group (Arbeitsgemeinschaft Gynäkologische Onkologie, AGO) has again published their yearly update on recommendations for the diagnosis and therapy of breast cancer. Literature was screened for new findings up to the beginning of 2008. Changes were incorporated in nearly all of the 25 chapters. Notably, duration and schedules of adjuvant endocrine therapy, updated adjuvant chemotherapy regimens, findings in plastic surgery, radiotherapy for node positive disease, evaluation of new prognostic and predictive factors, classification of lobular neoplasia, treatment of Paget's disease, inflammatory breast cancer, and sarcoma, as well as lapatinib and bevacizumab are discussed, only to mention a few. Using this easy accessible tool, high quality care can be given to the patient, standards can be communicated and justified to the health care system and new ideas will arise for clinical and pre-clinical development.
德国全国的医疗机构可能已经确立了某种形式的乳腺癌患者标准化治疗方案。然而,使标准与时俱进是一项相当复杂的工作,需要投入时间和财力。科学知识的更新换代迅速且数量众多。大多数医疗保健专业人员无法独自确保这种基于证据的诊断和治疗护理标准。德国妇科肿瘤学工作组(Arbeitsgemeinschaft Gynäkologische Onkologie,AGO)的乳腺委员会再次发布了其关于乳腺癌诊断和治疗建议的年度更新内容。对截至2008年初的文献进行了筛选以寻找新发现。几乎在25个章节中的所有内容都纳入了这些变化。值得注意的是,文中讨论了辅助内分泌治疗的持续时间和方案、更新的辅助化疗方案、整形手术的发现、淋巴结阳性疾病的放疗、新的预后和预测因素的评估、小叶肿瘤的分类、佩吉特病、炎性乳腺癌和肉瘤的治疗,以及拉帕替尼和贝伐单抗等,这里仅列举了其中一些。利用这个易于获取的工具,可以为患者提供高质量的护理,向医疗保健系统传达并说明标准,还会为临床和临床前发展带来新的思路。
Breast Care (Basel). 2022-8