Nayeem Asim, Elkhodair Samer, Jaiganesh Thiagarajan
St Georges Hospital, Blackshaw road, Tooting, SW17 0QT London UK.
Int J Emerg Med. 2010 Nov 6;3(4):465-8. doi: 10.1007/s12245-010-0250-4.
Acute severe methemoglobinaemia is an uncommon but life-threatening condition caused by a variety of oxidizing agents commonly used in both health care and industrial settings. Thus, recognition is important as it is readily treatable. The oxygen transport is compromised as a result of abnormal levels of oxidized haemoglobin, and this leads to skin discolouration and a variety of symptoms. Diagnostic confusion occurs as the oxygen saturations (SpO2) on the pulse oximeter are unreliable (Sharma V, Haber A. Acquired methaemoglobinaemia: a case report of benzocaine-induced methaemoglobinaemia and a review of the literature. Clin Pul Med. 2002;9(1):53-8). A case of severe methaemoglobinaemia due to self poisoning with barbicide is presented with a brief discussion of the patho-physiology and an overview of the treatment. A barbicidal overdose has never been reported before.
急性重度高铁血红蛋白血症是一种罕见但危及生命的病症,由医疗保健和工业环境中常用的多种氧化剂引起。因此,认识到这一点很重要,因为它很容易治疗。由于氧化血红蛋白水平异常,氧气运输受到损害,这会导致皮肤变色和各种症状。由于脉搏血氧仪上的血氧饱和度(SpO2)不可靠,会出现诊断混淆(Sharma V,Haber A. 获得性高铁血红蛋白血症:一例苯佐卡因引起的高铁血红蛋白血症病例报告及文献综述。临床肺科医学。2002;9(1):53 - 8)。本文介绍了一例因使用杀藻剂自杀中毒导致的严重高铁血红蛋白血症病例,并简要讨论了病理生理学和治疗概述。此前从未有过杀藻剂过量服用的报告。