Egiazaryan G G, Chernyshevskaya I A
Neurosci Behav Physiol. 1977 Jul-Sep;8(3):262-9. doi: 10.1007/BF01184068.
A comparative analysis was undertaken of the functional and structural maturation of peripheral pathways for the conduction of afferent impulses to the sensomotor cortex from muscle and skin receptors of the sciatic nerve during postnatal ontogeny in rabbits. The criterion of functional maturity of the fibers was their sensitivity to the blocking action of procaine when applied to muscular and cutaneous nerves. Structural maturation of peripheral nerve fibers was determined by the degree of their myelination. Successive blocking of fibers of muscular and cutaneous nerves by procaine was shown to depress certain components of the cortical evoked potential. As the animal develops, the sensitivity of its nerve fibers to procaine and the configuration of the evoked response are modified. Different peripheral projections, maturing at different times, participate in the organization of individual components of the cortical evoked potentials. This also takes place during maturation of peripheral afferent projections from muscular and cutaneous receptors.
对家兔出生后个体发育过程中，从坐骨神经的肌肉和皮肤感受器向感觉运动皮层传导传入冲动的外周通路的功能和结构成熟进行了比较分析。纤维功能成熟的标准是其对应用于肌肉和皮肤神经的普鲁卡因阻断作用的敏感性。外周神经纤维的结构成熟度由其髓鞘化程度决定。结果表明，用普鲁卡因连续阻断肌肉和皮肤神经的纤维会抑制皮层诱发电位的某些成分。随着动物的发育，其神经纤维对普鲁卡因的敏感性和诱发反应的构型会发生改变。不同时间成熟的不同外周投射参与了皮层诱发电位各个成分的组织。这也发生在来自肌肉和皮肤感受器的外周传入投射的成熟过程中。
