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[生物材料与血管移植物]

[Biomaterials and vascular grafts].

作者信息

Xiang Ping, Li Min

机构信息

College of Life Sciences, Fujian Normal University, Fuzhou 350108, China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Dec;27(6):1420-4.

Abstract

The latest articles concerning the vascular grafts made of biomaterials were retrieved and the data on application of electrospun biopolymer in small diameter vascular tissue engineering scaffolds were comprehensively analyzed. The biomaterials, including natural vascular, decellularized scaffolds and biopolymer in the field of vascular grafts were studied. But natural vascular grafts and decellularized scaffolds can not meet the requirements of small diameter vascular graft because of inadequate sources and potential immunogenicity, respectively. The small diameter vascular scaffolds prepared by electrospinning of biopolymer can optimally simulate the blood vessel structure and properties, and hence can present a better approach to acquiring small diameter vascular tissue engineering scaffolds.

摘要

检索了有关生物材料制成的血管移植物的最新文章,并全面分析了电纺生物聚合物在小直径血管组织工程支架中的应用数据。研究了血管移植物领域中的生物材料,包括天然血管、去细胞支架和生物聚合物。但是,天然血管移植物和去细胞支架分别由于来源不足和潜在的免疫原性而不能满足小直径血管移植物的要求。通过生物聚合物静电纺丝制备的小直径血管支架可以最佳地模拟血管结构和特性,因此可以提供一种更好的方法来获得小直径血管组织工程支架。

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