[脾胃调节针刺对糖尿病周围神经病变患者神经传导活动的影响]

[Effect of spleen-stomach regulation-needling on nerve conduction activity in patients with diabetic peripheral neuropathy].

作者信息

Ji Xue-qun, Wang Chun-mei, Zhang Ping, Zhang Xin, Zhang Zhi-long

机构信息

Department of Acu-moxibustion, The Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine, Tianjin 300120, China.

出版信息

Zhen Ci Yan Jiu. 2010 Dec;35(6):443-7.

PMID:21375019

Abstract

OBJECTIVE

To observe the effect of acupuncture on the nerve conduction function in patients with diabetic peripheral neuropathy.

METHODS

Eighty diabetic patients were equally randomized into acupuncture group and medication group. Uniform reinforcing and reducing manipulation of acupuncture for regulating both spleen and stomach was applied to bilateral Quchi (LI11), Hegu (LI4), Xuehai (SP10), Diji (SP8), Zhongwan (CV12), Zusanli (ST36), Yinlingquan (SP9), etc., for 30 min, once daily for 4 weeks. Patients of the medication group were treated with intramuscular injection of Mecobalamine (500 microg), once daily for 4 weeks. The sensory conduction velocity (SCV), motor conduction velocity (MCV), the amplitude and latency of the evoked potential of the tibial nerve were detected before and after the treatment by using an Electromyograph and Evoked Potential Equipment.

RESULTS

After the treatment, of the two 40 cases in the medication and acupuncture groups, 12 (30.0%) and 24 (60.0%) were cured basically, 12 (30.0%) and 10 (25.0%) experienced marked improvement in their symptoms, 9 (22.5%) and 4 (10.0%) were effective, and 7 (17.5%) and 2 (5.0%) failed in the treatment, with the total effective rates being 82.5% and 95.0% respectively. The therapeutic effect of the acupuncture group was significantly superior to that of the medication group (P < 0.05). In comparison with the ptre-treatment, the SCV, MCV, amplitude and latency of the evoked potential of the tibial nerve in the acupuncture group were improved significantly after the treatment (P < 0.05, P < 0.01). Compared with the medication group, the SCV, the amplitude and the latency of the tibial nerve in the acupuncture group were also improved significantly after the treatment (P < 0.05, P < 0.01).

CONCLUSION

Manipulation of acupuncture for regulating spleen-stomach function has a better effect on the conduction function of the tibial nerve than Mecobalamine in the treatment of diabetic patients with peripheral neuropathy.

摘要

目的

观察针刺对糖尿病周围神经病变患者神经传导功能的影响。

方法

将80例糖尿病患者随机分为针刺组和药物组，每组40例。针刺组采用提插补泻手法针刺双侧曲池（LI11）、合谷（LI4）、血海（SP10）、地机（SP8）、中脘（CV12）、足三里（ST36）、阴陵泉（SP9）等穴位，调节脾胃功能，留针30分钟，每日1次，连续治疗4周。药物组采用甲钴胺注射液（500微克）肌肉注射，每日1次，连续治疗4周。采用肌电图和诱发电位仪检测两组患者治疗前后胫神经感觉传导速度（SCV）、运动传导速度（MCV）、诱发电位波幅及潜伏期。

结果

治疗后，药物组40例中基本治愈12例（30.0%），显效12例（30.0%），有效9例（22.5%），无效7例（17.5%），总有效率为82.5%；针刺组基本治愈24例（60.0%），显效10例（25.0%），有效4例（10.0%），无效2例（5.0%），总有效率为95.0%。针刺组疗效明显优于药物组（P<0.05）。针刺组治疗后胫神经SCV、MCV、诱发电位波幅及潜伏期与治疗前比较，差异有统计学意义（P<0.05，P<0.01）；与药物组比较，差异亦有统计学意义（P<0.05，P<0.01）。