Department of Paediatric Surgery, St. John's Medical College Hospital, St. John's National Academy of Health Sciences, Bangalore, India.
J Pediatr Surg. 2011 Mar;46(3):e1-4. doi: 10.1016/j.jpedsurg.2010.10.024.
Segmental dilatation of the colon is a rare disorder of colonic motility in children, often presenting with severe constipation in older infants, children, and occasionally adults. It may mimic the commoner Hirschsprung disease clinicoradiologically but differs in that the ganglion cell morphology and distribution are typically normal in the colon. We report a neonate with segmental dilatation of the sigmoid colon who had an atypical clinical presentation and describe certain abnormalities in bowel histology (hypertrophied muscularis propria, nerve plexus, and ganglion cells located within the circular layer rather than the normal myenteric location), for the first time in the English literature.
结肠节段性扩张是儿童结肠运动障碍的一种罕见疾病，常表现为年长婴儿、儿童和偶尔成人的严重便秘。它在临床上和放射学上可能与更常见的先天性巨结肠病相似，但不同之处在于结肠的神经节细胞形态和分布通常正常。我们报告了一例乙状结肠节段性扩张的新生儿，其临床表现不典型，并首次在英文文献中描述了肠组织学的某些异常（肥大的肌层、神经丛和位于环形层而不是正常肌间位置的神经节细胞）。
