Bonn J, Gardiner G A, Shapiro M J, Sullivan K L, Levin D C
Department of Radiology, Jefferson Medical College, Philadelphia, PA.
Radiology. 1990 Mar;174(3 Pt 1):741-5. doi: 10.1148/radiology.174.3.2137633.
The safety and efficacy of the Palmaz balloon-expandable vascular stent and its effect on the results of percutaneous transluminal angioplasty (PTA) were assessed in a prospective study. Technical success was achieved in the placement of 34 of 35 stents (97%) in 27 common and external iliac artery lesions in 19 patients (23 limbs) who presented with disabling claudication, rest pain, or gangrene. Stent placement improved the angiographic results achieved by PTA alone in all 19 patients. Seventeen of 23 limbs (74%) had significant (greater than 20%) elevation of the ankle-arm index after combined angioplasty and stent placement, including nine limbs with occlusive outflow lesions. All 10 patients with continuous runoff distal to the stent and one patient with discontinuous runoff had resolution of their symptoms, remaining unchanged at a mean follow-up time of 6 months. There were three complications: One significantly altered the patient's hospital course, but none detracted from the achieved stent result. Stent placement is effective and does not significantly increase the complication rate of conventional iliac PTA. The current delivery system, however, may limit its utility.
在一项前瞻性研究中评估了帕尔马兹球囊扩张式血管支架的安全性和有效性及其对经皮腔内血管成形术（PTA）结果的影响。19例（23条肢体）出现致残性间歇性跛行、静息痛或坏疽的患者，其27处髂总动脉和髂外动脉病变中，35枚支架有34枚（97%）成功植入。支架植入改善了所有19例患者单纯PTA所取得的血管造影结果。血管成形术联合支架植入后，23条肢体中有17条（74%）踝臂指数显著升高（超过20%），其中9条肢体存在闭塞性流出道病变。支架远端有连续血流的所有10例患者和1例有间断血流的患者症状均得到缓解，平均随访6个月时情况保持不变。发生了3例并发症：1例显著改变了患者的住院病程，但均未影响支架植入的结果。支架植入有效，且未显著增加传统髂动脉PTA的并发症发生率。然而，目前的输送系统可能会限制其应用。
