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Discrepancy in the kinetics of total and active anti-thymocyte globulin blood concentrations in recipients of allogeneic hematopoietic stem cell transplantation.

作者信息

Yamane Akiko, Mori Takehiko, Kato Jun, Ono Yukako, Okamoto Shinichiro

机构信息

Division of Hematology, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

Novartis Pharma Program for Clinical Therapeutics of Hematologic Malignancy, Keio University School of Medicine, Tokyo, Japan.

出版信息

Int J Hematol. 2011 Mar;93(3):406-407. doi: 10.1007/s12185-011-0778-y. Epub 2011 Mar 8.

DOI:10.1007/s12185-011-0778-y
PMID:21380930
Abstract
摘要

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Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics of Immunosuppressants in Allogeneic Hematopoietic Cell Transplantation: Part II.异基因造血细胞移植中免疫抑制剂的药代动力学、药效学和药物基因组学：第二部分。
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本文引用的文献

1
Favorable outcomes of intravenous busulfan, fludarabine, and 400 cGy total body irradiation-based reduced-intensity conditioning allogeneic stem cell transplantation for acute myelogenous leukemia with old age and/or co-morbidities.对于年龄较大和/或合并症的急性髓系白血病患者，采用静脉注射白消安、氟达拉滨和 400cGy 全身照射的低强度预处理异基因干细胞移植具有良好的结果。
Int J Hematol. 2010 Sep;92(2):342-50. doi: 10.1007/s12185-010-0649-y. Epub 2010 Aug 10.
2
Low serum levels of total rabbit-IgG is associated with acute graft-versus-host disease after unrelated donor hematopoietic stem cell transplantation: results from a prospective study.低血清总兔IgG水平与非亲缘供者造血干细胞移植后的急性移植物抗宿主病相关：一项前瞻性研究结果
Biol Blood Marrow Transplant. 2009 Aug;15(8):996-9. doi: 10.1016/j.bbmt.2009.04.013.
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Total and active rabbit antithymocyte globulin (rATG;Thymoglobulin) pharmacokinetics in pediatric patients undergoing unrelated donor bone marrow transplantation.接受非亲属供体骨髓移植的儿科患者中兔抗胸腺细胞球蛋白（rATG；即胸腺球蛋白）的总药代动力学和活性药代动力学。
Biol Blood Marrow Transplant. 2009 Feb;15(2):274-8. doi: 10.1016/j.bbmt.2008.11.027.
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Mechanisms of action of antithymocyte globulin: old dogs with new tricks!抗胸腺细胞球蛋白的作用机制：老药新用！
Leuk Lymphoma. 2008 Sep;49(9):1664-7. doi: 10.1080/10428190802163321.
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Biol Blood Marrow Transplant. 2008 Jun;14(6):651-7. doi: 10.1016/j.bbmt.2008.03.006.
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Antithymocyte globulin pharmacokinetics in pediatric patients after hematopoietic stem cell transplantation.造血干细胞移植后儿科患者抗胸腺细胞球蛋白的药代动力学
J Pediatr Hematol Oncol. 2005 Oct;27(10):532-6. doi: 10.1097/01.mph.0000184575.00717.25.
7
Protective conditioning for acute graft-versus-host disease.急性移植物抗宿主病的保护性预处理
N Engl J Med. 2005 Sep 29;353(13):1321-31. doi: 10.1056/NEJMoa050642.
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Rabbit-immunoglobulin G levels in patients receiving thymoglobulin as part of conditioning before unrelated donor stem cell transplantation.在接受兔抗胸腺细胞球蛋白作为非亲缘供者干细胞移植预处理一部分的患者中的兔免疫球蛋白G水平。
Haematologica. 2005 Jul;90(7):931-8.
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Antilymphocyte/thymocyte globulin for graft versus host disease prophylaxis: efficacy and side effects.抗淋巴细胞/胸腺细胞球蛋白用于预防移植物抗宿主病：疗效与副作用
Bone Marrow Transplant. 2005 Feb;35(3):225-31. doi: 10.1038/sj.bmt.1704758.
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Pharmacokinetics and pharmacodynamics of anti-thymocyte globulin in recipients of partially HLA-matched blood hematopoietic progenitor cell transplantation.部分 HLA 配型相合的血液造血祖细胞移植受者中抗胸腺细胞球蛋白的药代动力学和药效学
Biol Blood Marrow Transplant. 2003 Jul;9(7):460-71. doi: 10.1016/s1083-8791(03)00127-7.