[Influence of carbon and nitrogen sources on biosynthesis of lycopene by Streptomyces globisporus 4Lcp].

The biosynthesis of lycopene by the strain Streptomyces globisporus 4Lcp has been studied at synthetic media with different sources of carbon and nitrogen. It has been shown that the highest yield of lycopene (2.0-3.0 microg/l), in case of cultivation in shacked flasks, has been observed when glycerol is used as a source of carbon and sodium or potassium nitrate as a source of nitrogen. Lower indices have been obtained when glucose, starch, sodium acetate and trisodium citrate are used as sources of carbon and ammonium chloride or ammonium nitrate as a nitrogen source. Such substrates as ethanol, sucrose, ammonium hydrophosphate or sulphate and carbamide have been shown to be inappropriate for lycopene production by the studied strain.