Macromolecules and Interfaces Institute, Virginia Polytechnic Institute, Blacksburg, Virginia 24061, United States.
Biomacromolecules. 2011 Apr 11;12(4):1106-15. doi: 10.1021/bm101448f. Epub 2011 Mar 23.
Cellulose esters containing adipates and other ester groups are synthesized by the reaction of commercially available cellulose esters in solution with the benzyl monoester of adipoyl chloride. The products, cellulose adipate esters in which the distal end of the adipate moiety is a benzyl ester, were easily converted to cellulose adipate derivatives by Pd-catalyzed hydrogenation. These cellulose adipate derivatives are promising biopolymers for drug delivery and other applications in which water-dispersion or swelling are desired.
通过在溶液中将市售纤维素酯与苯甲酰氯的单酯进行反应，合成了含有己二酸酯和其他酯基的纤维素酯。这些产物是纤维素己二酸酯，其己二酸酯部分的远端为苄基酯，通过 Pd 催化氢化可容易地转化为纤维素己二酸酯衍生物。这些纤维素己二酸酯衍生物是用于药物传递和其他需要水分散或溶胀的应用的有前途的生物聚合物。
