Division of Allergy and Clinical Immunology, Bnai-Zion Medical Center, Technion Faculty of Medicine, Haifa, Israel.
Acta Paediatr. 2011 Oct;100(10):e183-5. doi: 10.1111/j.1651-2227.2011.02257.x. Epub 2011 Mar 28.
The transition from milk protein-induced enterocolitis syndrome to IgE-mediated milk allergy is uncommon. Herein, we describe three infants that suffered from recurrent vomiting and restlessness in response to cow's milk formula with negative skin prick to milk and therefore diagnosed as milk protein-induced enterocolitis syndrome. After recovering and reintroducing cow's milk formula, they developed disseminated urticaria and positive skin prick test to cow milk compatible with IgE-mediated milk allergy.
An infant that recovers from cow milk food-induced enterocolitis syndrome might develop afterward IgE-mediated cow milk allergy.
从牛奶蛋白诱导的肠炎综合征到 IgE 介导的牛奶过敏的转变并不常见。在此，我们描述了 3 例婴儿在摄入牛奶配方奶粉后出现反复呕吐和烦躁，而牛奶皮肤点刺试验为阴性，因此被诊断为牛奶蛋白诱导的肠炎综合征。在恢复并重新引入牛奶配方奶粉后，他们出现了弥散性荨麻疹，且对牛奶的皮肤点刺试验为阳性，符合 IgE 介导的牛奶过敏。
从牛奶食物诱导的肠炎综合征中恢复的婴儿可能随后会发生 IgE 介导的牛奶过敏。
