Department of Functional Brain Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Japan.
Neurosci Res. 2011 Jun;70(2):144-54. doi: 10.1016/j.neures.2011.02.010. Epub 2011 Mar 4.
This article presents a hypothesis that the rostral premotor-subcortical networks may serve as a gateway between the cognitive and motor networks. Accumulating evidence has propelled an idea that motor and cognitive behaviors considerably share neural substrates and probably computational principles regardless of the species. Here I conducted a meta-analysis of previous neuroimaging studies on motor planning and different cognitive tasks (mental calculation, visuospatial processing and cognitive control), which showed overlap of all activations in the rostral premotor cortex, with a possible rostro-caudal functional gradient. It was also suggested that the rostral premotor areas might form circuits with specific portions of the cerebellum and the basal ganglia. The rostral premotor areas may provide context-dependent connectivity and mediate information flow between the cognitive and motor networks, thereby making the two networks operating interactively or independently.
本文提出了一个假设，即额前运动皮质下网络可能是认知和运动网络之间的一个连接点。越来越多的证据表明，无论物种如何，运动和认知行为都大量共享神经基质，可能还有计算原理。在这里，我对之前关于运动规划和不同认知任务（心算、视空间处理和认知控制）的神经影像学研究进行了荟萃分析，结果显示在额前运动皮质中所有激活都有重叠，可能存在一个从前往后的功能梯度。还提出了额前运动区可能与小脑和基底神经节的特定部位形成回路。额前运动区可能提供上下文相关的连接，并在认知和运动网络之间介导信息流，从而使两个网络可以进行交互或独立运作。
