Averbeck Bruno B, Battaglia-Mayer Alexandra, Guglielmo Carla, Caminiti Roberto
University College London, Institute of Neurology, Sobell Department of Motor Neuroscience and Movement Disorders, Box 28, Queen Square, London WC1N 3BG, UK.
J Neurophysiol. 2009 Sep;102(3):1911-20. doi: 10.1152/jn.00519.2009. Epub 2009 Jul 22.
Considerable information has been gathered on the anatomical connectivity within the parieto-frontal network of the primate brain. To examine the statistical regularities in this connectivity, we carried out hierarchical cluster analysis and found statistically significant clusters of areas: four in the parietal and six in the frontal lobe. Clusters were based on patterns of inputs from all cortical areas. Both parietal and frontal clusters were composed of sets of spatially contiguous architectonic areas. The four parietal clusters were composed of sets of anterior (somatosensory), dorsal, inferior, and medio-lateral parietal cortical areas. The six frontal clusters were composed of sets of dorsal premotor, ventral premotor, primary motor, cingulate motor, and dorsal and ventral prefrontal cortical areas. Furthermore, connectivity between frontal and parietal clusters was topographic and reciprocal. Thus we found substantial statistical structure and organization in the parieto-frontal network that gives a simplified but accurate description of this system.
关于灵长类大脑顶叶-额叶网络内的解剖连接性，已经收集了大量信息。为了研究这种连接性中的统计规律，我们进行了层次聚类分析，发现了具有统计学意义的区域簇：顶叶有四个，额叶有六个。这些簇是基于来自所有皮质区域的输入模式划分的。顶叶和额叶的簇均由空间上相邻的结构区域组成。四个顶叶簇由前（体感）、背侧、下侧和中外侧顶叶皮质区域组成。六个额叶簇由背侧运动前区、腹侧运动前区、初级运动区、扣带运动区以及背侧和腹侧前额叶皮质区域组成。此外，额叶和顶叶簇之间的连接是拓扑性的且相互的。因此，我们在顶叶-额叶网络中发现了大量的统计结构和组织，这对该系统给出了一个简化但准确的描述。
