Crowe S F, Hay D A
Department of Psychology, LaTrobe University, Bundoora, Victoria, Australia.
Neuropsychologia. 1990;28(1):9-16. doi: 10.1016/0028-3932(90)90082-y.
This study contends that males with the fragile X syndrome feature problems in the visuospatial sphere as compared with Down syndrome males matched on vocabulary ability. Fragile X males suffer impairments of constructional functions, as demonstrated by their poor performance on block construction tests and on drawing tasks. These problems exist in association with visuoperceptive impairments, including the inability to reliably estimate angular relationships (Judgement of Line Orientation). They have shortened Digit and Corsi spans, and may feature some deficits in left hand co-ordination. The observation of a pervasive non-verbal deficit may also apply to carrier females, who despite functioning at an overall higher level, feature a similar pattern of deficits. It is possible that the deficit in non-dominant hemisphere functioning may be a pathognomonic feature of the chromosomal abnormality.
本研究认为，与在词汇能力上匹配的唐氏综合征男性相比，患有脆性X综合征的男性在视觉空间领域存在问题。脆性X男性存在建构功能障碍，这在积木搭建测试和绘图任务中的不佳表现中得到了证明。这些问题与视觉感知障碍相关，包括无法可靠地估计角度关系（线方向判断）。他们的数字广度和科西广度缩短，并且可能在左手协调方面存在一些缺陷。对普遍存在的非语言缺陷的观察也可能适用于携带者女性，她们尽管整体功能水平较高，但也存在类似的缺陷模式。非优势半球功能的缺陷可能是这种染色体异常的一个特征性表现。
