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极性疗法治疗乳腺癌放疗患者癌因性疲乏的随机对照初步研究。

Polarity Therapy for cancer-related fatigue in patients with breast cancer receiving radiation therapy: a randomized controlled pilot study.

机构信息

University of Rochester, Rochester, NY 14642, USA.

出版信息

Integr Cancer Ther. 2011 Mar;10(1):27-37. doi: 10.1177/1534735410397044. Epub 2011 Mar 7.

Abstract

BACKGROUND

Cancer-related fatigue (CRF) is the most frequently reported side effect of cancer and its treatment. In previous research, Polarity Therapy (PT), an energy therapy, was shown to reduce CRF in patients receiving radiation. This study reports on a small randomized clinical trial designed to collect preliminary data on the efficacy of PT compared with an active control (massage) and passive control (standard care) for CRF among cancer patients receiving radiation therapy.

METHODS

Forty-five women undergoing radiation therapy for breast cancer were randomized to 1 of 3 weekly treatment conditions. Patients received standard clinical care, 3 modified massages, or 3 PT treatments. CRF and health-related quality of life (HRQL) were assessed during baseline and the 3 intervention weeks.

RESULTS

TResults show CRF ratings were reduced after PT. The effect sizes for PT versus modified massage and versus standard care were small when using the primary measure of CRF (Brief Fatigue Inventory) and large when using the secondary measure of CRF (Daily CRF Diaries).The effect size was medium when assessing the benefit of PT on maintaining HRQL compared with standard care with very little difference between the PT and modified massage conditions. Patients' feedback showed that both the modified massage and PT treatments were deemed useful by radiation patients.

CONCLUSION

The present pilot randomized clinical trial supports previous experimental research showing that PT, a noninvasive and gentle energy therapy, may be effective in controlling CRF. Further confirmatory studies as well as investigations of the possible mechanisms of PT are warranted.

摘要

背景

癌症相关疲劳(CRF)是癌症及其治疗最常报告的副作用。在之前的研究中,极性疗法(PT),一种能量疗法,已被证明可减轻接受放射治疗的患者的 CRF。本研究报告了一项小型随机临床试验的结果,该试验旨在收集有关 PT 与活动对照(按摩)和被动对照(标准护理)在接受放射治疗的癌症患者中的 CRF 疗效的初步数据。

方法

45 名接受乳腺癌放射治疗的女性随机分为 3 种每周治疗条件之一。患者接受标准临床护理、3 种改良按摩或 3 种 PT 治疗。在基线和 3 个干预周期间评估 CRF 和健康相关生活质量(HRQL)。

结果

结果显示,PT 后 CRF 评分降低。使用 CRF 的主要测量指标(简要疲劳量表)和次要测量指标(每日 CRF 日记)时,PT 与改良按摩和标准护理相比的效应大小较小,而与标准护理相比,PT 对维持 HRQL 的益处的效应大小为中等。患者的反馈表明,改良按摩和 PT 治疗都被放射治疗患者认为是有用的。

结论

本初步随机临床试验支持先前的实验研究结果,表明非侵入性和温和的能量疗法 PT 可能有效控制 CRF。需要进一步的确认性研究以及对 PT 可能机制的研究。

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