Research Institute Havelhöhe at the Hospital Gemeinschaftskrankenhaus Havelhöhe, Berlin, Germany.
Institute for Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
Trials. 2021 Dec 2;22(1):866. doi: 10.1186/s13063-021-05869-3.
The majority of breast cancer patients suffer from persistent impairments after completion of their primary oncological therapy. Cancer-related fatigue (CRF) in particular is a multidimensional syndrome having a profound negative impact on the quality of life. To counter CRF symptoms, physical activities are suggested as first-line interventions, mind-body therapies have been shown to be effective, and music therapy can also reduce anxiety and stress in breast cancer patients. Tango therapy that combines various elements can have an impact on physical, psychological, and cognitive abilities and could therefore have a beneficial effect on breast cancer patients. The purpose of this study is to investigate whether a 6-week tango module is suited as a therapeutic approach for people after primary breast cancer therapy to favorably influence their quality of life, especially CRF levels.
Sixty patients with a diagnosis for stage I-III breast cancer 12-48 months before enrollment and with CRF (age > 18) will be recruited and randomized 1:1 to a tango or a waiting-list group. Movement concepts using elements of Argentine tango (self-awareness, musical and spatial perception, self-perception, playfulness, shared experience) will be examined with the participants during six consecutive weekly 1-h tango sessions. The primary outcome will be the improvement of CRF (German version of the Cancer Fatigue Scale), and the secondary outcomes will be the improvement in sleep quality (Pittsburgh Sleep Quality Index) and quality of life (EORTC-QLQ-C30). Patient-reported outcomes will be measured at baseline and 6 weeks later; follow-up will be performed 6, 12, and 24 months after baseline. An evaluation will be performed by means of descriptive data analyses.
Argentine tango, as a music-based movement therapy, can influence different skills and may improve several outcomes. The therapeutic use of Argentine tango in the care of breast cancer patients has not yet been reported. It is anticipated that participants receiving the tango module will have improved CRF, sleep, and quality of life scores compared to a waitlist control.
German Clinical Trials Registry (DRKS) DRKS00021601 . Retrospectively registered on 21 August 2020.
大多数乳腺癌患者在完成主要的肿瘤学治疗后仍存在持续性的功能障碍。尤其是癌症相关疲劳（CRF），这是一种多维综合征，对生活质量有深远的负面影响。为了缓解 CRF 症状，建议将体育活动作为一线干预措施，身心疗法已被证明是有效的，音乐疗法也可以减轻乳腺癌患者的焦虑和压力。而融合了多种元素的探戈疗法可能对身体、心理和认知能力产生影响，因此可能对乳腺癌患者有有益的效果。本研究旨在探讨为期 6 周的探戈模块是否适合作为原发性乳腺癌治疗后患者的治疗方法，以有利地影响他们的生活质量，特别是 CRF 水平。
将招募 60 名被诊断患有 I-III 期乳腺癌且在入组前 12-48 个月的患者，且患有 CRF（年龄＞18 岁），并将他们随机分为探戈组或候补组 1:1。将在连续六周的每周 1 小时的探戈课程中，与参与者一起检查使用阿根廷探戈元素的运动概念（自我意识、音乐和空间感知、自我感知、趣味性、共同体验）。主要结局将是 CRF（德语版癌症疲劳量表）的改善，次要结局将是睡眠质量（匹兹堡睡眠质量指数）和生活质量（EORTC-QLQ-C30）的改善。将在基线和 6 周后测量患者报告的结果；在基线后 6、12 和 24 个月进行随访。将通过描述性数据分析进行评估。
阿根廷探戈作为一种基于音乐的运动疗法，可以影响不同的技能，并可能改善多种结果。阿根廷探戈在乳腺癌患者护理中的治疗应用尚未有报道。预计接受探戈模块的参与者与候补对照组相比，CRF、睡眠和生活质量评分将得到改善。
德国临床试验注册处（DRKS）DRKS00021601。于 2020 年 8 月 21 日回顾性注册。
