Haruki T, Arai T, Nakamura H, Nosaka K, Shomori K, Ito H
General Thoracic Surgery, Tottori University Hospital, Yonago, Japan.
Thorac Cardiovasc Surg. 2011 Mar;59(2):128-30. doi: 10.1055/s-0030-1250086. Epub 2011 Mar 7.
Pulmonary epithelioid hemangioendothelioma (PEH) is a relatively uncommon neoplasm of vascular origin with a low or intermediate grade of malignancy. We present a case of a 28-year-old female with multiple pulmonary nodules which were diagnosed as PEH by video-assisted thoracoscopic surgery (VATS) biopsy. In addition, we performed an immunohistochemical analysis for placenta growth factor (PlGF) and a strong positivity for PlGF observed, suggesting that the PlGF may play some role in the tumorigenesis of PEH.
肺上皮样血管内皮瘤（PEH）是一种相对罕见的血管源性肿瘤，恶性程度为低或中度。我们报告一例28岁女性，有多个肺结节，经电视辅助胸腔镜手术（VATS）活检诊断为PEH。此外，我们对胎盘生长因子（PlGF）进行了免疫组织化学分析，观察到PlGF呈强阳性，提示PlGF可能在PEH的肿瘤发生中起一定作用。
