Panje W R, Dobleman T J
Department of Otolaryngology, Head Neck Surgery, Pritzker School of Medicine, University of Chicago, Ill.
Arch Otolaryngol Head Neck Surg. 1990 Apr;116(4):470-4. doi: 10.1001/archotol.1990.01870040092021.
Radiation-induced skin cancers can be difficult to diagnose and treat. Typically, a patient who has received orthovoltage radiotherapy for disorders such as acne, eczema, tinea capitis, skin tuberculosis, and skin cancer can expect that aggressive skin cancers and chronic radiodermatitis may develop subsequently. Cryptic facial cancers can lead to metastases and death. Prophylactic widefield excision of previously irradiated facial skin that has been subject to multiple recurrent skin cancers is suggested as a method of deterring future cutaneous malignancy and metastases. The use of tissue expanders and full-thickness skin grafts offers an expedient and successful method of subsequent reconstruction.
辐射诱发的皮肤癌可能难以诊断和治疗。通常，接受过深部X线放疗治疗痤疮、湿疹、头癣、皮肤结核和皮肤癌等疾病的患者，随后可能会发生侵袭性皮肤癌和慢性放射性皮炎。隐匿性面部癌症可导致转移和死亡。建议对曾接受多次复发性皮肤癌放疗的面部皮肤进行预防性广泛切除，作为预防未来皮肤恶性肿瘤和转移的一种方法。使用组织扩张器和全厚皮片移植提供了一种便捷且成功的后续重建方法。
