Boćkowski Leszek, Smigielska Kuzia Joanna, Sobaniec Wojciech, Sendrowski Krzysztof
Department of Pediatric Neurology and Rehabilitation, Medical University of Białystok, Poland.
Przegl Lek. 2010;67(9):688-91.
The Interictal abnormalities of cerebral information processing in migraine were found by studying different modality-specific evoked and event related potentials, mostly visual and auditory. In this study we focused on short-latency somatosensory evoked potentials (SEP) in children and adolescents suffering from migraine with and without aura.
The study group consisted 111 of children and adolescents at the age of 7-18 years: 27 of them suffered from migraine with aura, 36 of them suffered from migraine without aura, 48 subjects have episodic tension-type headache. SEPs was performed interictally at least two days after the last headache attack.
There were no significant differences in the latency averages of SEP components between all migraneurs and tension-type headache subjects. However, N9 and N13 latency averages were significantly shorter in migraine without aura group compared with migraine with aura and tensiom type headaches. We did not find any significant correlations for either headache type between evoked potentials parametrs and illness duration, unilateral localisation of pain, migraine in family and aura.
In concert with similar studies in adult migraineurs, our findings showed no disturbances of somatosensory information processing in children with migraine with aura and without aura. The diagnosis of migraine in children actually remains predominantly based on medical history. However, electrophysiological techniques allow the study of some of the structures in vivo and enlarge our knowledge on controversial aspects of migraine pathophysiology.
通过研究不同模态特异性诱发电位和事件相关电位（主要是视觉和听觉），发现偏头痛患者存在发作间期脑信息处理异常。在本研究中，我们聚焦于有先兆和无先兆偏头痛儿童及青少年的短潜伏期体感诱发电位（SEP）。
研究组由111名7至18岁的儿童及青少年组成：其中27人患有先兆偏头痛，36人患有无先兆偏头痛，48名受试者患有发作性紧张型头痛。在最后一次头痛发作至少两天后进行发作间期SEP检测。
所有偏头痛患者与紧张型头痛受试者的SEP各成分潜伏期平均值无显著差异。然而，无先兆偏头痛组的N9和N13潜伏期平均值显著短于有先兆偏头痛组和紧张型头痛组。我们未发现诱发电位参数与头痛类型、病程、疼痛单侧定位、家族性偏头痛及先兆之间存在任何显著相关性。
与成人偏头痛患者的类似研究一致，我们的研究结果表明，有先兆和无先兆偏头痛儿童的体感信息处理无紊乱。儿童偏头痛的诊断实际上仍主要基于病史。然而，电生理技术可用于体内某些结构的研究，并扩展我们对偏头痛病理生理学争议方面的认识。
