Department of General Practice/Medical Clinic III, Dresden Medical School, Dresden University of Technology, Dresden, Germany.
J Altern Complement Med. 2011 Mar;17(3):225-30. doi: 10.1089/acm.2009.0673. Epub 2011 Mar 8.
Migraine is one of the most prevalent neurological disorders in Europe, severely affecting ability to work and quality of life. Medical therapies are considered to be the "gold standard" of treatment. This study addresses osteopathic treatment for acute therapy or prophylactic therapy as an alternative to traditional therapies.
Forty-two (42) female patients with migraine were randomized into an intervention group (n = 21) and a control group (n = 21). Outcomes were evaluated with three questionnaires before the treatment (t1) and 6 months later (t2).
The intervention group received five 50-minute osteopathic manipulative treatments (OMT) over a 10-week period. The control group did not receive OMT, sham treatment, or physical therapy. Patients of this group only filled the questionnaires. Both groups continued with previously prescribed medication.
The Migraine Disability Assessment (MIDAS) and Short Form-36 (SF-36) questionnaires as well as a German "pain questionnaire" were used to assess pain intensity, the impact of migraine on daily life and health-related quality of life (HRQoL), and the number of days subjects suffered from migraine.
Three (3) of the eight HRQoL domains of the SF-36 form in the intervention group showed significant improvement (from t1 to t2), with a general betterment exhibited in the other domains. The total MIDAS score, pain intensity, and disturbance in occupation due to migraine as well as number of days of disablements were also significantly reduced. The control group showed insignificant differences in these areas.
This study affirms the effects of OMT on migraine headache in regard to decreased pain intensity and the reduction of number of days with migraine as well as working disability, and partly on improvement of HRQoL. Future studies with a larger sample size should reproduce the results with a control group receiving placebo treatment in a long-term follow-up.
偏头痛是欧洲最常见的神经疾病之一，严重影响工作能力和生活质量。医学治疗被认为是“金标准”的治疗方法。本研究探讨了整骨疗法作为传统疗法的替代疗法，用于急性治疗或预防性治疗。
42 名偏头痛女性患者随机分为干预组（n=21）和对照组（n=21）。在治疗前（t1）和 6 个月后（t2）使用三个问卷评估结果。
干预组在 10 周内接受 5 次 50 分钟的整骨手法治疗（OMT）。对照组未接受 OMT、假治疗或物理治疗。该组的患者仅填写问卷。两组均继续服用先前开的药物。
使用偏头痛残疾评估（MIDAS）和简明 36 项健康调查（SF-36）问卷以及德国“疼痛问卷”评估疼痛强度、偏头痛对日常生活和健康相关生活质量（HRQoL）的影响，以及偏头痛发作的天数。
干预组的 SF-36 表单中的 8 个 HRQoL 领域中的 3 个（从 t1 到 t2）显示出显著改善，其他领域也表现出总体改善。总 MIDAS 评分、疼痛强度、偏头痛对职业的干扰以及残疾天数也显著减少。对照组在这些方面没有明显差异。
本研究证实了 OMT 对偏头痛头痛的疗效，可降低疼痛强度，减少偏头痛发作天数和残疾天数，并在一定程度上改善 HRQoL。未来应在长期随访中，使用安慰剂治疗的对照组重复这项研究。
