Cardiology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
J Cardiovasc Electrophysiol. 2011 Aug;22(8):915-21. doi: 10.1111/j.1540-8167.2011.02020.x. Epub 2011 Mar 8.
Usefulness of the interval between the last pacing stimulus and the last entrained atrial electrogram (SA) minus the tachycardia ventriculoatrial (VA) interval in the differential diagnosis of supraventricular tachycardias with long (>100 ms) VA intervals has not been prospectively studied in a large series of patients. Our objective was to assess the usefulness of the difference SA-VA in diagnosing the mechanism of those tachycardias in patients without preexcitation. The results were compared with those obtained using the corrected return cycle (postpacing interval-tachycardia cycle length-atrioventricular [AV] nodal delay).
We included 314 consecutive patients with inducible sustained supraventricular tachycardias with VA intervals >100 ms undergoing an electrophysiologic study. Atrial tachycardias were excluded. Tachycardia entrainment was attempted through pacing trains from right ventricular apex. The SA-VA difference and the corrected return cycle were calculated for every patient. Electrophysiologic study revealed 82 atypical AV nodal reentrant tachycardias (AVNRT) and 237 AV reentrant tachycardias (AVRT) using septal (n = 91) or free-wall (n = 146) accessory pathways (APs). A SA-VA difference >110 ms identified an atypical AVNRT with sensitivity, specificity, positive and negative predictive values of 99%, 98%, 95%, and 99.5%, respectively. Similarly, these values were 88%, 83%, 77%, and 92% for SA-VA difference <50 ms in identifying AVRT through a septal versus free-wall AP. The SA-VA difference showed higher accuracy in septal AP identification than that obtained using the corrected return cycle.
The difference SA-VA provides a simpler electrophysiologic maneuver that reliably differentiates atypical AVNRT from AVRT regardless of concealed AP location.
在长(>100ms)VA 间期的室上性心动过速中,最后起搏刺激与最后被夺获的心房电图(SA)之间的间期减去心动过速室房(VA)间期在鉴别诊断中的作用尚未在大量患者的前瞻性研究中进行研究。我们的目的是评估在没有预激的情况下,这些心动过速的机制诊断中 SA-VA 差值的有用性。将结果与使用校正回传周期(起搏后间期心动过速周期长度-房室结[AVN]延迟)获得的结果进行比较。
我们纳入了 314 例连续的可诱导持续性 VA 间期>100ms 的室上性心动过速患者进行电生理研究。排除了心房性心动过速。通过右心室心尖起搏刺激尝试心动过速夺获。为每位患者计算 SA-VA 差值和校正回传周期。电生理研究显示,82 例非典型房室结折返性心动过速(AVNRT)和 237 例房室折返性心动过速(AVRT),使用间隔部(n=91)或游离壁(n=146)附加旁路(APs)。SA-VA 差值>110ms 可识别非典型 AVNRT,其敏感性、特异性、阳性预测值和阴性预测值分别为 99%、98%、95%和 99.5%。同样,对于通过间隔部 vs. 游离壁 AP 识别 AVRT 的 SA-VA 差值<50ms,这些值分别为 88%、83%、77%和 92%。SA-VA 差值在识别间隔部 AP 方面比校正回传周期更准确。
SA-VA 差值提供了一种更简单的电生理操作,可可靠地区分非典型 AVNRT 与 AVRT,无论隐匿性 AP 位置如何。