多尿型脑死亡器官捐献者的血清血管加压素（AVP）水平

Serum vasopressin (AVP) levels in polyuric brain-dead organ donors.

作者信息

Hohenegger M, Vermes M, Mauritz W, Redl G, Sporn P, Eiselsberg P

机构信息

Institute of General and Experimental Pathology, University of Vienna, Austria.

出版信息

Eur Arch Psychiatry Neurol Sci. 1990;239(4):267-9. doi: 10.1007/BF01738582.

DOI:10.1007/BF01738582

PMID:2138551

Abstract

Hydromineral metabolism and serum arginine-vasopressin (AVP) levels were investigated in 11 patients who sustained brain death. They showed various degrees of polyuria with low osmolality and low fractional sodium excretion. Urine osmolality was always below that of serum, and AVP levels were between 1.3 and 50.0 pg/ml vs 0.7-8.0 pg/ml in ten normal subjects. Thus central diabetes insipidus was excluded. A renal mechanism inducing water diuresis has to be assumed. The type of renal lesion, however, remains unclear.

摘要

对11例脑死亡患者的水盐代谢及血清精氨酸加压素（AVP）水平进行了研究。他们表现出不同程度的低渗性多尿和低尿钠排泄分数。尿渗透压始终低于血清渗透压，AVP水平在1.3至50.0 pg/ml之间，而10名正常受试者的AVP水平为0.7 - 8.0 pg/ml。因此排除了中枢性尿崩症。必须假定存在一种导致水利尿的肾脏机制。然而，肾脏病变的类型仍不清楚。